Traditional use
Used in traditional Malaysian and Indonesian medicine for centuries as a tonic for vitality, energy, and male health. Known locally as 'Malaysian ginseng'.
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Tongkat Ali
Eurycoma longifolia
Family · Simaroubaceae
Malaysia, Indonesia, Thailand
Tongkat Ali is a flowering plant native to Southeast Asian rainforests, valued in traditional medicine for its adaptogenic properties. The root contains quassinoids, particularly eurycomanone, which contribute to its bioactivity.
At a glance
Tongkat Ali (Eurycoma longifolia) is supplied by Phyto-Medichem as a standardised extract from our manufacturing facility. Marker compound: Eurycomanone (C20H24O9). Available now for commercial supply. Sourced from Malaysia, Indonesia, Thailand. Per-batch Certificate of Analysis from our in-house HPLC analytical laboratory.
| Marker compound | Eurycomanone |
|---|---|
| Molecular formula | C20H24O9 |
| PubChem CID | 13936691 |
| Botanical family | Simaroubaceae |
| Source region | Malaysia, Indonesia, Thailand |
| Pipeline stage | Commercial Supply |
| Commercial status | Commercial |
| Catalogue SKU | COM-TKA-001 |
Marker compound
Eurycomanone
C20H24O9
The principal characterised compound for Tongkat Ali. Structure data and identifiers sourced from PubChem.
View on PubChem (CID 13936691)Profile
Compound profile
Active compounds
EurycomanoneEurycomanolEurycomalactoneQuassinoidsAlkaloidsGlycosaponins
Mechanisms of action
- Hypothalamic-pituitary-gonadal axis modulation
- Cortisol regulation
- Phosphodiesterase inhibition
- Antioxidant activity
Applications
Energy and fatigueHormonal balanceAthletic performanceStress adaptationHealthy ageing
Development status
Commercial supply via eurycomanone-characterised extract. Analytical methods established for eurycomanone quantification and quassinoid profiling.
Regulatory notes
Generally recognised as safe. Widely approved as a dietary supplement ingredient across major markets including USA, EU, and ASEAN.
Sourcing & sustainability
Sourced from cultivators in Southeast Asia with attention to sustainability and traceability from harvest through extraction.
Key research
Peer-reviewed literature
Selected reviews and primary studies indexed on PubMed / PMC. The mechanism-of-action framings on this page are drawn from peer-reviewed pharmacology; consult these sources for the underlying evidence and methodology.
- PMCReview on a Traditional Herbal Medicine, Eurycoma longifolia Jack (Tongkat Ali): Its Traditional Uses, Chemistry, Evidence-Based Pharmacology and Toxicology
Comprehensive evidence-based review of chemistry, pharmacology, and safety.
- PMCEurycoma longifolia: an overview on the pharmacological properties for the treatment of common cancer
Mechanistic review covering quassinoid pharmacology.
- PubMedAn evidence-based systematic review of tongkat ali (Eurycoma longifolia) by the Natural Standard Research Collaboration
Systematic review of clinical and preclinical evidence.
For research and ingredient-supply context only
Mechanism, traditional-use, and application descriptions on this page are presented as pharmacological research context for B2B formulators, buyers, and licensing partners. They do not constitute medical advice, regulatory claims, or a guarantee of therapeutic effect, and downstream product claims remain the responsibility of the formulator under their jurisdiction's regulations. See the regulatory notes block above for compound-specific market context.
From our perspectives
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